Epigenetic Clock Development Corporation

Organization Overview

Epigenetic Clock Development Corporation is located in Torrance, CA. According to its NTEE Classification (H05) the organization is classified as: Research Institutes & Public Policy Analysis, under the broad grouping of Medical Research and related organizations. As of 12/2022, Epigenetic Clock Development Corporation employed 6 individuals. This organization is an independent organization and not affiliated with a larger national or regional group of organizations. Epigenetic Clock Development Corporation is a 501(c)(3) and as such, is described as a "Charitable or Religous organization or a private foundation" by the IRS.

For the year ending 12/2022, Epigenetic Clock Development Corporation generated $3.6m in total revenue. All expenses for the organization totaled $3.4m during the year ending 12/2022.

Mission & Program ActivityExcerpts From the 990 Filing

TAX YEAR

2022

Describe the Organization's Mission:

Part 3 - Line 1

THE EPIGENETIC CLOCK DEVELOPMENT FOUNDATION ("CLOCK FOUNDATION") WAS FORMED TO ENABLE RIGOROUS MEDICAL RESEARCH ON AGING AND LONGEVITY. OUR RESEARCH MAINLY INVOLVES USE AND DEVELOPMENT OF NEW AGING BIOMARKERS KNOWN AS EPIGENETIC CLOCKS FOR TESTING THE EFFECTIVENESS OF LONGEVITY TREATMENTS WITHIN PRECLINICAL AND CLINICAL STUDIES.

Describe the Organization's Program Activity:

Part 3 - Line 4a

INTERNAL RESEARCH PROGRAM: HIRING OF ADDITIONAL CLOCK FOUNDATION TEAM MEMBERS WE HIRED AN ADDITIONAL PHD BIOSTATISTICIAN, ALONG WITH ADDITIONAL PART-TIME OPERATIONAL, ADMINISTRATION, AND FINANCE STAFF. WE CONTINUED TO WORK CLOSELY WITH OUR SCIENTIFIC ADVISORY BOARD, ESPECIALLY ON THE DEVELOPMENT OF RIGOROUS APPROACHES FOR EPIGENETIC CLOCK TESTING. EXCLUSIVE UCLA IP LICENSE COMPLETED AN EXCLUSIVE LICENSE TO THE HORVATH IP PORTFOLIO WAS OBTAINED IN JUNE 2021. NO ADDITIONAL SUBLICENSES OR OUTLICENSING AGREEMENTS HAVE BEEN ENTERED INTO, ALTHOUGH WE ENTERED INTO SEVERAL RESEARCH COLLABORATION AGREEMENTS WITH GROUPS THIS YEAR.


OTHER PROGRAM SERVICES


EXTERNAL RESEARCH COLLABORATIONS: MANY INTERVENTIONAL STUDIES COMPLETED ONE OF THE MOST SIGNIFICANT PROMISES OF EPIGENETIC CLOCKS IS TO ACT AS A RELIABLE BIOMARKER TO EVALUATE PUTATIVE LONGEVITY TREATMENTS. WE CONDUCTED MANY NEW INTERVENTIONAL STUDIES, FOR CLINICAL TRIALS AND ALSO PRECLINICAL STUDIES, SOME WITH EXCITING EFFECTS AND OTHERS WITH MEDIOCRE OR NEGATIVE RESULTS. THIS INCLUDES STUDIES ON PLASMAPHARESIS, YOUNG PLASMA TREATMENT, STEM CELL EXOSOMES, UMBILICAL CORD PLASMA, AND A SENOLYTIC GENE THERAPY. MECHANISMS OF AGING STUDIES ONGOING ANOTHER KEY APPLICATION OF EPIGENETIC CLOCKS IS TO HELP ENABLE MECHANISTIC STUDIES, INCLUDING THE LINK OF EPIGENETIC AGING TO OTHER AGING HALLMARKS. EXCITING MECHANISTIC STUDIES THIS PAST YEAR INCLUDED ONES ON ERCC1 PROGERIA MODELS, BONE MARROW TRANSPLANTS, AND PROGERIA CELL LINES.


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Board, Officers & Key Employees

Name (title)Compensation
Robert Brooke
Executive Di
$120,000
Stefan Horvath
Director, Ch
$106,042
Dean Prissman
Director
$0

Financial Statements

Statement of Revenue
Federated campaigns$0
Membership dues$0
Fundraising events$0
Related organizations$0
Government grants $0
All other contributions, gifts, grants, and similar amounts not included above$0
Noncash contributions included in lines 1a–1f $0
Total Revenue from Contributions, Gifts, Grants & Similar$0
Total Program Service Revenue$1,580,545
Investment income $116
Tax Exempt Bond Proceeds $0
Royalties $0
Net Rental Income $0
Net Gain/Loss on Asset Sales $0
Net Income from Fundraising Events $0
Net Income from Gaming Activities $0
Net Income from Sales of Inventory $0
Miscellaneous Revenue$0
Total Revenue $3,593,807

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