American Institute For Cancer Research

ADVANCES RESEARCH, EDUCATION AND COMMUNITY PROGRAMS FOR CANCER PREVENTION AND SURVIVORSHIP.

SEE SCHEDULE O. EDUCATIONEDUCATION PROGRAMSTHE AMERICAN INSTITUTE FOR CANCER RESEARCH (AICR) CHAMPIONS THE LATEST AND MOST AUTHORITATIVE SCIENTIFIC RESEARCH ON CANCER PREVENTION AND SURVIVAL THROUGH DIET, WEIGHT AND PHYSICAL ACTIVITY SO THAT WE CAN HELP PEOPLE MAKE INFORMED LIFESTYLE CHOICES TO REDUCE THEIR RISK. WE WANT TO LIVE IN A WORLD WHERE NO ONE DEVELOPS A PREVENTABLE CANCER. EDUCATION: AICR'S MESSAGEAICR'S EDUCATION PROGRAMS ARE EVIDENCE-BASED. THIS EVIDENCE COMES FROM BOTH THE RESEARCH WE FUND, AND THE CONCLUSIONS DRAWN IN OUR SCIENTIFIC REPORTS. FROM THESE FINDINGS WE PRODUCE EDUCATIONAL MATERIALS TO MEET A WIDE VARIETY OF NEEDS, ACROSS ALL STAGES OF THE CANCER CONTINUUM. AICR NEWSLETTERIN FISCAL YEAR (FY) 2021, AICR DISTRIBUTED ALMOST 1.2 MILLION COPIES OF ITS NEWSLETTER TO SUPPORTERS. EACH QUARTERLY ISSUE IS FILLED WITH ARTICLES ON RESEARCH, PHYSICAL ACTIVITY, WEIGHT MANAGEMENT AND NUTRITION, INCLUDING RECIPES RELATED TO REDUCING CANCER RISK FOR PREVENTION AND HEALTHY SURVIVORSHIP. THE PRACTICAL TIPS, ADVICE AND FEATURED STORIES ARE ALL MADE POSSIBLE BY AICR'S GENEROUS SUPPORTERS. EACH ISSUE IS REVIEWED BY AN ADVISORY GROUP OF CLINICIANS, REGISTERED DIETITIANS, RECIPE DEVELOPERS AND CANCER RESEARCHERS. BROCHURES AND FACT SHEETSDEVELOPED TO PUT THE LATEST CANCER RESEARCH FINDINGS IN A CONCISE FORMAT, AICR'S BROCHURES, LEAFLETS AND FACT SHEETS OFFER MANY DIFFERENT AUDIENCES OUR EMPOWERING MESSAGE THAT WE CAN TAKE STEPS TO REDUCE OUR OWN CANCER RISK. FOLLOWING THE LAUNCH OF OUR THIRD EXPERT REPORT IN MAY 2018, ALL THESE RESOURCES WERE REVIEWED AND UPDATED TO REFLECT THE MOST CURRENT SCIENTIFIC EVIDENCE.IN FY21, WE OFFERED 22 DIFFERENT BROCHURE TITLES AND 11 FACT SHEETS FOR CANCER PREVENTION AND CANCER SURVIVORSHIP. INDIVIDUALS CAN ORDER SINGLE FREE COPIES; HEALTH PROFESSIONALS AND MEDICAL CENTERS (E.G., HOSPITALS, CANCER CLINICS, ETC.) CAN MAKE BULK PURCHASES. AICR ALSO DISTRIBUTES BROCHURES AT CONFERENCES, EVENTS AND HEALTH FAIRS. IN FY21, AICR DISTRIBUTED OVER 41,000 BROCHURES AND OTHER PUBLICATIONS.HEALTH AIDSAICR PRODUCES HEALTH AIDS INCLUDING CHARTS, TEAR SHEETS, MAGNETS, A CALENDAR AND MORE TO TURN LOWERING CANCER RISK INTO A "HANDS-ON" EXPERIENCE. INDIVIDUALS CAN ORDER SINGLE FREE COPIES; HEALTH PROFESSIONALS AND MEDICAL CENTERS (HOSPITALS, CANCER CLINICS, ETC.) CAN MAKE BULK PURCHASES. AICR ALSO DISTRIBUTES HEALTH AIDS AT CONFERENCES, EVENTS AND HEALTH FAIRS. IN FY21, AICR DISTRIBUTED MORE THAN 4,000 HEALTH AIDS.FOODS THAT FIGHT CANCER CALENDARIN FY21, WE DISTRIBUTED 4,181 "FOODS THAT FIGHT CANCER" CALENDARS, WITH 12 MONTHLY MESSAGES ON PREVENTING CANCER AND 12 RECIPES. AICR WEBSITETHE GOAL OF THE AICR WEBSITE (WWW.AICR.ORG) IS TO INSPIRE USERS TO TAKE CONTROL OF THEIR HEALTH USING RESEARCH-BACKED CANCER PREVENTION AND SURVIVORSHIP RESOURCES. THE WEBSITE OFFERS UPDATED INFORMATION ON AICR RESEARCH; HEALTHY, CANCER-PROTECTIVE RECIPES AND FITNESS TIPS; AND A HOST OF INTERACTIVE TOOLS AND RESOURCES ON THE SCIENCE OF LOWERING CANCER RISK. FOLLOWING THE LAUNCH OF OUR THIRD EXPERT REPORT IN MAY 2018, AICR CONTINUED TO UPDATE, EDIT AND ADD CONTENTINCLUDING TWO WEBINARS IN FY21TO ENSURE THE WEBSITE REFLECTS THE LATEST SCIENTIFIC EVIDENCE. IN FY21, AICR'S WEBSITE RECEIVED OVER 1.5 MILLION USERS (UNIQUE VISITORS) AND THE TOTAL NUMBER OF PAGE VIEWS EXCEEDED 2.8 MILLION.AICR'S WEBSITE ALSO INCLUDES INSPIRING STORIES OF IMPACT. THESE ARE TESTIMONIALS BY HEALTH PROFESSIONALS WHO REGULARLY USE AICR'S RESOURCES TO BUILD HEALTHIER COMMUNITIES THROUGH CANCER CENTERS, SURVIVORSHIP PROGRAMS AND MORE. THE AUTHORS RANGED FROM A FAMILY NURSE PRACTITIONER TO AN OCCUPATIONAL THERAPIST TO RDNS AND WERE FROM ALL PARTS OF THE COUNTRY INCLUDING RURAL, SUBURBAN AND URBAN AREAS. SOME OF THEM WORKED AT LARGE MEDICAL CENTERS LIKE NYU AND CEDARS-SINAI. WE ALSO SHARED THEIR STORIES IN THE MONTHLY CANCER FOCUS. THERE ARE ALSO TESTIMONIALS BY PEOPLE WHO HAVE BEEN DIRECTLY AFFECTED BY CANCER OR KNOW SOMEONE WHO HAS BEEN AFFECTED BY CANCER, AND HOW THEY HAVE USED AICR'S RESOURCES TO HELP THEMSELVES OR OTHERS NAVIGATE CANCER FROM DIAGNOSIS THROUGH SURVIVORSHIP. FREE E-PUBLICATIONSAICR HAS DEVELOPED A LIBRARY OF E-PUBLICATIONS THAT DELIVER THE LATEST INFORMATION ON LOWERING CANCER RISK STRAIGHT TO SUBSCRIBERS' INBOXES. OUR E-PUBLICATIONS ARE REVIEWED BY CANCER RESEARCHERS, CLINICIANS, DIETITIANS AND AICR STAFF. IN TANDEM WITH THE LAUNCH OF THE NEW WEBSITE, AICR REDESIGNED THE E-PUBLICATIONS TO GIVE THEM A MODERN LOOK THAT IS MORE VISUALLY APPEALING. THE THREE E-PUBLICATIONS WERE ALSO RENAMED TO BETTER REFLECT THEIR PURPOSES: AICR NEWS IS A MONTHLY E-NEWSLETTER EMPHASIZING THE "TAKE-HOME" MESSAGE: HOW CAN I START LIVING FOR LOWER CANCER RISK TODAY? THOSE LOOKING TO DIG DEEPER INTO THE RESEARCH CAN DO SO BY SUBSCRIBING TO RESEARCH UPDATE. AT THE CLOSE OF FY21 THIS MONTHLY DIGEST OF BREAKING NEWS AND CURRENT RESEARCH IN THE FIGHT AGAINST CANCER HAD OVER 25,000 SUBSCRIBERS INTERESTED IN THE SCIENCE OF CANCER RISK, AS WELL AS HEALTH PROFESSIONALS LOOKING TO STAY CURRENT. RECHARGE IS A MONTHLY E-PUBLICATION THAT SERVES THE CANCER SURVIVOR COMMUNITY. WITH CONTENT RELATED TO RESEARCH, RECIPES, FOODS AND SURVIVOR WELLNESS, THIS PUBLICATION AIMS TO HELP CANCER PATIENTS NAVIGATE THEIR CANCER JOURNEY. AS OF JULY 2021, OVER 11,000 PEOPLE HAVE SUBSCRIBED TO RECHARGE.TOWARDS THE END OF FY21, WE DECIDED TO CONSOLIDATE AND MERGE THE THREE NEWSLETTERS INTO ONE TO LIMIT THE NUMBER OF EMAILS GOING TO OUR SUBSCRIBERS' INBOXES. THE NEW MONTHLY NEWSLETTERCANCER FOCUSENCOMPASSES THE THREE AREAS THAT WERE THE FOCUS OF THE SEPARATE E-PUBS. IN THE NEWLY BRANDED NEWSLETTER, WE KEEP THE CONTENT NEWSY AND USEFUL FOR OUR SUBSCRIBERS WITH ARTICLES ON ANTI-INFLAMMATORY DIETS AND LATEST INSIGHTS FROM CANCER RESEARCH STUDIES. AS OF SEPTEMBER 2021, OVER 88,000 PEOPLE HAVE SUBSCRIBED TO AICR CANCER FOCUS.AICR HEALTHY RECIPES IS FOR THOSE LOOKING FOR WAYS TO BRING THE RESEARCH HOME WITH QUICK, EASY AND DELICIOUS CANCER-PROTECTIVE MEALS. ALL MONTHLY RECIPES ARE SPECIALLY CRAFTED WITH CANCER PREVENTION AND HEALTHY SURVIVORSHIP IN MIND AND FOLLOW AICR'S RECIPE GUIDELINES. AS OF SEPTEMBER 2021, OVER 30,000 PEOPLE HAVE SUBSCRIBED TO AICR HEALTHY RECIPES.AICR BLOG AND SOCIAL MEDIATHE AICR BLOG (AICR.ORG/RESOURCES/BLOG) SPEAKS TO SUPPORTERS; CANCER PATIENTS, SURVIVORS AND CAREGIVERS; HEALTH PROFESSIONALS; THE MEDIA AND THE GENERAL PUBLIC. THE AICR BLOG IS ONE WAY AICR ENGAGES IN AN ONGOING DISCUSSION ABOUT RESEARCH AND SEPARATES CANCER MYTHS FROM CANCER FACTS, ESPECIALLY THOSE THAT ARE HOT TOPICS IN THE MEDIA. IT IS WHERE WE SHARE OUR TAKE ON CURRENT NEWS AND ENCOURAGE READERS TO POST COMMENTS. IN FY21, THE AICR BLOG RECEIVED OVER 415,000 USERS (UNIQUE VISITORS), AND NEARLY 560,000 PAGE VIEWS. FACEBOOK AND TWITTER HAVE HISTORICALLY BEEN IMPORTANT COMMUNICATION CHANNELS FOR AICR TO SHARE MESSAGES WITH A WIDE AND DIVERSE AUDIENCE. IN ADDITION TO FACEBOOK AND TWITTER, AICR INCREASED SOCIAL MEDIA EFFORTS IN FY21 TO HELP GROW OUR BRAND ON INSTAGRAM, LINKEDIN, PINTEREST AND YOUTUBE. AT THE END OF FY21, AICR GAINED A TOTAL OF 5,848 SOCIAL MEDIA FOLLOWERS FOR 13.4% GROWTH COMPARED TO FY20. OVER THE COURSE OF FY21 AICR SOCIAL MEDIA CHANNELS HAD A TOTAL OF 2,671,687 IMPRESSIONS AND 145,247 ENGAGEMENTS. SOCIAL MEDIA TOTAL NUMBER OF FOLLOWERS (AS OF 9/30/2021): 47,737 (TWITTER, FACEBOOK, INSTAGRAM, LINKEDIN, PINTEREST). INSTAGRAM (@CANCERPREVENTION) SAW THE LARGEST GROWTH IN FY21 WITH 3,418 NEW FOLLOWERS, TOTALING 7,516 FOLLOWERS AT THE END OF SEPTEMBER 2021. THIS IS AN 82.9% INCREASE COMPARED TO FY20. ON AVERAGE, INSTAGRAM CONTENT REACHED 765 USERS DAILY. AT THE CLOSE OF FY21, AICR'S FACEBOOK PAGE HAD 24,020 FOLLOWERS AND ON AVERAGE, OUR CONTENT REACHED OVER 4,000 USERS DAILY. TWITTER (@AICRTWEETS) HAD 7,251 FOLLOWERS, LINKEDIN HAD 6,875 AND PINTEREST HAD 2,075.CANCER PREVENTION MONTH AWARENESS CAMPAIGNIN FEBRUARY 2021, AICR LAUNCHED OUR ANNUAL CANCER PREVENTION MONTH CAMPAIGN TO RAISE AWARENESS THAT 40% OF CANCERS CAN BE PREVENTED AND PROVIDE EMPOWERING MESSAGES TO HELP CANCER SURVIVORS TAKE CONTROL OF THEIR HEALTH.WE ENCOURAGED PEOPLE TO "TAKE THE TEN AND LAUNCHED OUR NEW ONLINE TOOL (AICR'S HEALTHY10 CHALLENGE) TO HELP PEOPLE CHANGE THEIR LIFESTYLE HABITS AND PUT AICR'S CANCER PREVENTION RECOMMENDATIONS INTO ACTION. THE HEALTHY10 CHALLENGE IS A FREE, 10-WEEK INTERACTIVE PROGRAM DESIGNED TO HELP INDIVIDUALS IMPROVE THEIR DIET, NUTRITION, PHYSICAL ACTIVITY AND WEIGHT FOR LOWER CANCER RISK AND BETTER OVERALL HEALTH. AT THE END OF FEBRUARY, ALMOST 2,000 INDIVIDUALS SIGNED UP FOR THE CHALLENGE.

SEE SCHEDULE O.RESEARCHAICR RESEARCH PROGRAMSSCIENTIFIC STUDY OF THE RELATIONSHIP OF DIET, PHYSICAL ACTIVITY AND WEIGHT MANAGEMENT TO CANCER RISK AND SURVIVORSHIP CONTINUES TO BE THE PRIMARY FOCUS OF AMERICAN INSTITUTE FOR CANCER RESEARCH (AICR) RESEARCH INVESTMENT AND ACTIVITIES. EVIDENCE SHOWS THAT WEIGHT MANAGEMENT, PHYSICAL ACTIVITY, FOOD AND NUTRITION PLAY IMPORTANT ROLES IN CANCER PREVENTION, TREATMENT AND SURVIVORSHIP. RESEARCH SHOWS THAT APPROXIMATELY 40% OF ALL CANCERS COULD BE PREVENTED IF EVERYONE REACHED AND MAINTAINED A HEALTHY WEIGHT, FOLLOWED THE RECOMMENDATIONS FOR REGULAR PHYSICAL ACTIVITY, CONSUMED A HEALTHY DIET, AVOIDED USE OF TOBACCO PRODUCTS AND FOLLOWED APPROPRIATE SCREENING AND VACCINATION GUIDELINES. AICR IS UNIQUE IN ITS FOCUS ON PREVENTING CANCER AND IMPROVING SURVIVAL THROUGH DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY. WE COLLATE AND INTERPRET THE LATEST AND MOST AUTHORITATIVE GLOBAL SCIENTIFIC RESEARCH ON THE LINKS BETWEEN CANCER AND DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY. WE THEN TRANSLATE OUR FINDINGS INTO PRACTICAL, CLEAR, EVIDENCE-BASED RECOMMENDATIONS ON CANCER PREVENTION FOR USE BY HEALTH PROFESSIONALS, INDIVIDUALS AND GOVERNMENTS WORLDWIDE.IN TOTAL, THROUGH FY21, AICR HAS COMMITTED MORE THAN $110 MILLION FOR HUNDREDS OF INDIVIDUAL RESEARCH PROJECTS AT UNIVERSITIES, HOSPITALS AND RESEARCH CENTERS. AICR PIONEERED THE FUNDING OF RESEARCH EXAMINING DIET AND CANCER AND WAS THE FIRST ORGANIZATION TO DEVOTE ITSELF TO STUDYING THE ROLE OF DIET AND OTHER LIFESTYLE FACTORS IN LOWERING CANCER RISK. THE RESEARCH THAT WE HAVE FUNDED HAS HELPED TRANSFORM THE ONCE-RADICAL NOTIONTHAT EVERYDAY CHOICES CAN DRAMATICALLY REDUCE CANCER RISKINTO A UNIVERSALLY ACCEPTED MEDICAL FACT AND PUBLIC HEALTH POLICY.OUR MULTI-FACETED INVESTMENT IN RESEARCH CONTINUES ACROSS SEVERAL CORE ACTIVITIESAICR GRANT PROGRAMTHE AICR GRANT PROGRAM IS DEDICATED TO FUNDING RESEARCH ON CANCER PREVENTION, TREATMENT AND SURVIVAL RELATED TO DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY. IN DECEMBER 2020, AICR HELD A WEBINAR ABOUT OUR GRANT PROGRAM TO STIMULATE INTEREST AND GIVE GUIDANCE FOR APPLICATIONS. OVER 200 RESEARCHERS ATTENDED, AND DR. CONNIE ROGERS FROM PENN STATE UNIVERSITY PRESENTED ABOUT HER EXPERIENCE AS A FUNDED SCIENTISTS AND A PEER REVIEWER. IN THE 2021 GRANT CYCLE, WE RECEIVED 97 LETTERS OF INTENT (LOIS): 36 ON CANCER PREVENTION, 44 ON CANCER SURVIVORSHIP AND 17 COVERING BOTH AREAS. WE INVITED 46 APPLICANTS TO SUBMIT FULL APPLICATIONS AND RECEIVED 42 FOR OUR GRANT PANEL TO REVIEW AND DISCUSS.ALL APPLICATIONS ARE SUBJECTED TO RIGOROUS PEER REVIEW. FOR THE 2021 GRANT CYCLE, WE WELCOMED A NEW CHAIR TO OUR GRANT REVIEW PANEL, DR. JAMES FLEET, THE MARGARET MCKEAN LOVE ENDOWED PROFESSOR OF NUTRITION, CELLULAR, AND MOLECULAR SCIENCE AT THE UNIVERSITY OF TEXAS AT AUSTIN. OUR CO-CHAIR WAS DR. LINDA COOK, CO-LEADER, CANCER CONTROL RESEARCH PROGRAM, UNIVERSITY OF NEW MEXICO COMPREHENSIVE CANCER CENTER. THE GRANT REVIEW PANEL INCLUDED 10 ADDITIONAL EXPERTS WITH THE DEPTH AND BREADTH OF EXPERTISE TO EVALUATE THE SCIENTIFIC MERIT AND IMPACT OF THE PROPOSED RESEARCH. DUE TO THE RESTRICTIONS IMPOSED BY THE COVID-19 PANDEMIC, THE GRANT REVIEW PANEL MEETING WAS CONDUCTED IN A HYBRID FORMAT WITH 7 MEMBERS JOINING US IN-PERSON AND THE OTHER MEMBERS ATTENDING BY VIDEO CONFERENCE.REVIEWERS-JUSTIN BROWN, PHD, PENNINGTON BIOMEDICAL RESEARCH CENTER-ANDREW CHAN, MD, MPH, HARVARD MEDICAL SCHOOL-CARRIE DANIEL-MACDOUGALL, PHD, MD ANDERSON CANCER CENTER-CHRISTINA DIELI-CONWRIGHT, PHD, MPH, DANA-FARBER CANCER INSTITUTE-JOANNE ELENA, PHD, MPH, NATIONAL INSTITUTES OF HEALTH -ROBERT NATIVIDAD FUENTES, PHD, MD ANDERSON CANCER CENTER-ERIK NELSON, PHD, UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN-THOMAS O'CONNELL, PHD, INDIANA UNIVERSITY -CONNIE ROGERS, PHD, PENNSYLVANIA STATE UNIVERSITY-PAUL SPAGNUOLO, PHD, UNIVERSITY OF GUELPHFUNDED GRANTS1. BREAST ADIPOCYTE HYPERTROPHY: A NOVEL BIOMARKER TO PREDICT BREAST CANCER SURVIVAL. CAROLINE DIORIO, PHD, UNIVERSITE LAVAL, QUEBEC, CANADA 2. INVESTIGATING THE IMMUNOLOGIC BASIS OF THE OBESITY PARADOX IN RENAL CELL CARCINOMA. A. ARI HAKIMI, MD, THE SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH, NEW YORK CITY, NY3. COFFEE AND CAFFEINE METABOLITES AND DISEASE PROGRESSION IN MEN ENROLLED ON ACTIVE SURVEILLANCE FOR PROSTATE CANCER. JUSTIN GREGG, MD, UNIVERSITY OF TEXAS M.D. ANDERSON CANCER CENTER, HOUSTON, TX4. PERSONALIZED FEEDBACK OF WEARABLE BIOLOGICAL SENSOR DATA TO PROMOTE ACTIVE LIVING IN CANCER SURVIVORS. YUE LIAO, MPH, PHD, CPH, THE UNIVERSITY OF TEXAS AT ARLINGTON, ARLINGTON, TX 5. DIET-MICROBIOTA-HOST INTERACTIONS MEDIATING ANTI-TUMOR IMMUNE RESPONSES IN COLORECTAL CANCER. WENDY GARRETT, MD, PHD, HARVARD T. H. CHAN SCHOOL OF PUBLIC HEALTH, BOSTON, MA6. LONG-CHAIN ACYL-COA SYNTHETASES AND N-MYRISTOYLTRANSFERASES MEDIATED METABOLIC PATHWAY PROMOTES HIGH-SATURATED FATTY ACID DIET ACCELERATED PROSTATE CANCER. HOUJIAN CAI, PHD, UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC, ATHENS, GAMARILYN GENTRY FELLOWSHIP AT THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (UNC)THE AICR MARILYN GENTRY FELLOWSHIP PROGRAM IN NUTRITION AND CANCER AT THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL WAS CREATED TO DEVELOP TOMORROW'S LEADERS IN NUTRITION RESEARCH IN RELATION TO CANCER. FELLOWS RECEIVE TWO YEARS OF STRUCTURED MENTORING WHILE PLANNING AND CONDUCTING RESEARCH. THEY DEVELOP A BODY OF DATA THAT WILL HELP THEM COMPETE SUCCESSFULLY FOR GRANT FUNDING IN THE FUTURE. THIS PROGRAM HAS PRODUCED SEVERAL GRADUATES WHO HAVE ENTERED THE NUTRITION-CANCER FIELD. AICR HAS ALSO FUNDED A DISTINGUISHED PROFESSORSHIP AT UNC TO CHAIR THIS PROGRAM. IN ADDITION, THE AICR-WCRF INSTITUTE FOR THE ADVANCED STUDY OF DIET, NUTRITION AND CANCER IS HOUSED WITHIN THE MICHAEL HOOKER RESEARCH CENTER ON THE UNC CAMPUS. THESE FACILITIES INCLUDE THREE LABORATORIES DEDICATED TO RESEARCHING THE ROLE OF DIET AND NUTRITION IN THE CAUSATION, PREVENTION AND TREATMENT OF CANCER. THE PAST RECIPIENTS OF THE MARILYN GENTRY FELLOWSHIP ARE:2001-2003: SUSAN STECK2002-2004: PHILIPPE THUILLIER2005-2007: ERIC PARK2006-2007: MIHALIS PANAGIOTIDIS2007-2009: BECKY CLEVELAND2007-2009: ZUZANA DROBNA2010-2012: XUESONG HAN2011-2014: PATRICK BRADSHAW2015-2018: EMMA ALLOTT2019-2021: XIMENA BUSTAMANTE-MARIN (FUNDED BY RELATED ENTITY WCRF)AICR EXPERT REPORTSSINCE 2007, AICR AND ITS INTERNATIONAL AFFILIATE, THE WORLD CANCER RESEARCH FUND (WCRF), HAVE WORKED TOGETHER ON THE CONTINUOUS UPDATE PROJECT (CUP). THE CUP HAS BUILT ON THE SYSTEMATIC LITERATURE REVIEW CONDUCTED FOR OUR 2007 SECOND EXPERT REPORT FOOD, NUTRITION, PHYSICAL ACTIVITY, AND THE PREVENTION OF CANCER: A GLOBAL PERSPECTIVE. IN 2018, AICR AND WCRF PUBLISHED DIET, NUTRITION, PHYSICAL ACTIVITY AND CANCER: A GLOBAL PERSPECTIVE, THE THIRD EXPERT REPORT TO UPDATE BOTH THE ASSESSMENT OF THE EVIDENCE FOR THE IMPACT OF EACH FACTOR ON CANCER RISK AND REVISE THE CANCER PREVENTION RECOMMENDATIONS THE CUP PROVIDES THROUGH TIMELY REVIEWS AND EXPERT PANEL ASSESSMENTS OF THE AVAILABLE PEER-REVIEWED EVIDENCE. THE CUP REPORTS HAVE IDENTIFIED EMERGING RESEARCH AREAS AND KNOWLEDGE GAPS THAT COULD BE ADDRESSED WITHIN OUR GRANT PROGRAM. EQUALLY, NEW DATA GENERATED FROM STUDIES FUNDED THROUGH OUR GRANT PROGRAM ARE INCLUDED IN THE CUP REVIEWS. THUS, AICR'S RESEARCH GRANT PROGRAMS AND THE CUP ACT SYNERGISTICALLY TO STRENGTHEN THE SCIENTIFIC EVIDENCE ON THE IMPACT OF DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY ON CANCER PREVENTION AND CONTROL.IN 2020, THE CUP HAS EMBARKED ON A PROCESS OF EVALUATION AND STRATEGIC PLANNING, TERMED THE CUP TRANSITION, WITH A PANEL OF INTERNATIONAL EXPERTS TO DETERMINE THE OPTIMAL DIRECTIONS FOR FUTURE RESEARCH IN THIS FIELD. THIS PROCESS CONTINUED THROUGH 2021, CONCLUDING WITH THE DEVELOPMENT OF A NEW STRATEGY THAT WILL BE OPERATIONALIZED IN 2022. CONCURRENTLY, THE CUP TRANSITION PANEL REVIEWED THE COMPLETED SYSTEMATIC LITERATURE REVIEWS ON MEDICAL OUTCOMES AND QUALITY OF LIFE IN BREAST CANCER SURVIVORS AND SUBMITTED SEVERAL MANUSCRIPTS FOR PUBLICATION IN PEER-REVIEWED JOURNALS.