Cancer Prevention Initiative Inc is located in Dallas, TX. The organization was established in 2015. According to its NTEE Classification (H30) the organization is classified as: Cancer Research, under the broad grouping of Medical Research and related organizations. This organization is an independent organization and not affiliated with a larger national or regional group of organizations. Cancer Prevention Initiative Inc is a 501(c)(3) and as such, is described as a "Charitable or Religous organization or a private foundation" by the IRS.
For the year ending 12/2022, Cancer Prevention Initiative Inc generated $257.1k in total revenue. This represents a relatively dramatic decline in revenue. Over the past 7 years, the organization has seen revenues fall by an average of (30.5%) each year. All expenses for the organization totaled $18.4k during the year ending 12/2022. As we would expect to see with falling revenues, expenses have declined by (38.4%) per year over the past 7 years. You can explore the organizations financials more deeply in the financial statements section below.
Since 2017, Cancer Prevention Initiative Inc has awarded 13 individual grants totaling $2,369,880. If you would like to learn more about the grant giving history of this organization, scroll down to the grant profile section of this page.
Form
990
Mission & Program ActivityExcerpts From the 990 Filing
TAX YEAR
2022
Describe the Organization's Mission:
Part 3 - Line 1
CANCER PREVENTION INITIATIVE, INC. (CPI) IS A NONPROFIT CORPORATION WHOSE MISSION IS TO ACCELERATE THE DISCOVERY AND DEVELOPMENT OF NEW MEDICINES THAT PREVENT CANCER.
Describe the Organization's Program Activity:
Part 3 - Line 4a
IN 2022, THE CANCER PREVENTION INITIATIVE (CPI) RESEARCH PROGRAMS PROGRESSED, AND CPI CONTINUED TO GROW AND DEVELOP. THE CPI SCIENTIFIC TEAM CONTINUED TO MONITOR AND SUPPORT SCIENTIFIC PROGRESS ON MULTI-YEAR PROGRAMS. CPI'S RESEARCH GRANT RECIPIENTS HAVE ADVANCED TOWARDS GREATER UNDERSTANDING OF PREVENTING INHERITED CANCERS. ONGOING PROJECTS INCLUDE CLEVELAND CLINIC, WHERE INVESTIGATORS SEEK TO IDENTIFY PROTEINS UNIQUELY AND HIGHLY EXPRESSED IN BREAST CANCER OF BRCA1 MUTATION CARRIERS. IDENTIFICATION OF THESE UNIQUE PROTEINS IS AN IMPORTANT LINK FOR DEVELOPING PREVENTATIVE VACCINES. ALSO CONTINUING IS A PROJECT WITH MEMORIAL SLOAN KETTERING CANCER CENTER TO GENERATE A ROBUST CELLULAR ASSAY THAT WOULD ALLOW FOR THE SCREENING OF HUNDREDS OF COMPOUNDS TO IDENTIFY DETERMINANTS OF LOSS OF HETEROZYGOSITY (LOH) OF BRCA GENES. LOH IS A MAJOR DRIVER IN CANCER INITIATION, AND DISCOVERY OF COMPOUNDS THAT CAUSE LOH CAN BE KEY FOR PREVENTION DISCOVERIES. OTHER ONGOING PROJECTS INCLUDE HARVARD'S BETH ISRAEL DEACONESS MEDICAL CENTER WHERE THEY ARE WORKING TO IDENTIFY CANCER RISK PREDICTORS IN THE REPRODUCTIVE EPITHELIUM IN BRCA MUTATION CARRIERS, AND WORK AT THE UNIVERSITY OF TORONTO TO SCREEN FOR DRUGS THAT CAN RESTORE NORMAL BRCA1 FUNCTION TO BRCA1 DEFICIENT CELLS. AN INTERNATIONAL COLLABORATION HAS CO-DEVELOPED A CANDIDATE VACCINE FOR THE PREVENTION OF TRIPLE NEGATIVE BREAST CANCERS IN PATIENTS WHO HAVE INHERITED A BRCA1 MUTATION.
EDUCATION AND COMMUNITY ENGAGEMENT PROGRAMS: AS WE MOVE CLOSER TO OUR GOAL OF ERADICATING ALL CANCERS THROUGH PREVENTATIVE MEDICINES, WE BELIEVE THAT EDUCATING THE PUBLIC AND RAISING AWARENESS ABOUT INHERITED CANCER SYNDROMES WILL INSPIRE MORE INDIVIDUALS TO TAKE PROACTIVE, LIFE-SAVING PREVENTIVE MEASURES. ONE OF THE GOALS IS TO ENHANCE THE SCIENTIFIC REACH OF THE ORGANIZATION AND RAISE AWARENESS ON CANCER PREVENTION TO A BROADER AUDIENCE OF PATIENTS, ADVOCATES AND DONORS. THUS, REGULAR UPDATES ON SCIENTIFIC AND MEDICAL RESEARCH ADVANCES, RECENT CLINICAL TRIALS, AND INTERVIEWS WITH EXPERTS IN CANCER PREVENTION ARE PUBLISHED ON WEB-BASED PLATFORMS. WE ALSO CONDUCT AN ANNUAL SCIENTIFIC SYMPOSIUM WITH ALL THE RESEARCHERS WE FUND AND OTHER SCIENTISTS WORKING ON CANCER PREVENTION.
Name (title) | Role | Hours | Compensation |
---|---|---|---|
Theodora Ross President & Chief Scientific Officer | OfficerTrustee | 10 | $0 |
Howard Janzen Board Chair; Chief Financial Officer | OfficerTrustee | 3 | $0 |
Kirk Patrick Secretary, Trustee | OfficerTrustee | 0.5 | $0 |
Jan Livingston-Mokhtari Trustee | Trustee | 0.5 | $0 |
Douglas Hager Trustee, Sr. Vice President, Project Management And Operations | Trustee | 10 | $0 |
Joi Morris Trustee | Trustee | 5 | $0 |
Statement of Revenue | |
---|---|
Federated campaigns | $0 |
Membership dues | $0 |
Fundraising events | $0 |
Related organizations | $0 |
Government grants | $0 |
All other contributions, gifts, grants, and similar amounts not included above | $245,219 |
Noncash contributions included in lines 1a–1f | $0 |
Total Revenue from Contributions, Gifts, Grants & Similar | $245,219 |
Total Program Service Revenue | $0 |
Investment income | $11,849 |
Tax Exempt Bond Proceeds | $0 |
Royalties | $0 |
Net Rental Income | $0 |
Net Gain/Loss on Asset Sales | $0 |
Net Income from Fundraising Events | $0 |
Net Income from Gaming Activities | $0 |
Net Income from Sales of Inventory | $0 |
Miscellaneous Revenue | $0 |
Total Revenue | $257,068 |
Statement of Expenses | |
---|---|
Grants and other assistance to domestic organizations and domestic governments. | $0 |
Grants and other assistance to domestic individuals. | $0 |
Grants and other assistance to Foreign Orgs/Individuals | $0 |
Benefits paid to or for members | $0 |
Compensation of current officers, directors, key employees. | $0 |
Compensation of current officers, directors, key employees. | $0 |
Compensation to disqualified persons | $0 |
Other salaries and wages | $0 |
Pension plan accruals and contributions | $0 |
Other employee benefits | $0 |
Payroll taxes | $0 |
Fees for services: Management | $0 |
Fees for services: Legal | $0 |
Fees for services: Accounting | $2,375 |
Fees for services: Lobbying | $0 |
Fees for services: Fundraising | $0 |
Fees for services: Investment Management | -$13 |
Fees for services: Other | $0 |
Advertising and promotion | $0 |
Office expenses | $3,367 |
Information technology | $5,837 |
Royalties | $0 |
Occupancy | $0 |
Travel | $0 |
Payments of travel or entertainment expenses for any federal, state, or local public officials | $0 |
Conferences, conventions, and meetings | $0 |
Interest | $0 |
Payments to affiliates | $0 |
Depreciation, depletion, and amortization | $3,590 |
Insurance | $2,405 |
All other expenses | $0 |
Total functional expenses | $18,418 |
Balance Sheet | |
---|---|
Cash—non-interest-bearing | $1,165 |
Savings and temporary cash investments | $14,413 |
Pledges and grants receivable | $0 |
Accounts receivable, net | $0 |
Loans from Officers, Directors, or Controlling Persons | $0 |
Loans from Disqualified Persons | $0 |
Notes and loans receivable | $0 |
Inventories for sale or use | $0 |
Prepaid expenses and deferred charges | $6,676 |
Net Land, buildings, and equipment | $0 |
Investments—publicly traded securities | $1,025,357 |
Investments—other securities | $0 |
Investments—program-related | $0 |
Intangible assets | $8,585 |
Other assets | $0 |
Total assets | $1,056,196 |
Accounts payable and accrued expenses | $93 |
Grants payable | $356,078 |
Deferred revenue | $0 |
Tax-exempt bond liabilities | $0 |
Escrow or custodial account liability | $0 |
Loans and other payables to any current Officer, Director, or Controlling Person | $0 |
Secured mortgages and notes payable | $0 |
Unsecured mortgages and notes payable | $0 |
Other liabilities | $0 |
Total liabilities | $356,171 |
Net assets without donor restrictions | $235,261 |
Net assets with donor restrictions | $464,764 |
Capital stock or trust principal, or current funds | $0 |
Paid-in or capital surplus, or land, building, or equipment fund | $0 |
Retained earnings, endowment, accumulated income, or other funds | $0 |
Total liabilities and net assets/fund balances | $1,056,196 |
Over the last fiscal year, Cancer Prevention Initiative Inc has awarded $480,000 in support to 3 organizations.
Grant Recipient | Amount |
---|---|
MEMORIAL SLOAN KETTERING CANCER CENTER PURPOSE: The objective of this project is to generate a robust cellular assay that would allow for the screening of hundreds of compounds to identify determinants of Loss of Heterozygosity (LoH) of BRCA genes. LoH is a major driver in cancer initiation. | $150,000 |
CLEVELAND CLINIC FOUNDATION PURPOSE: The objective of this project is to identify proteins uniquely and highly expressed in breast cancer of BRCA1 mutation carriers. Identification of these proteins can be key to developing preventative vaccines. | $150,000 |
UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER PURPOSE: Scientific and administrative oversight of all Cancer Prevention Initiative programs. | $180,000 |