Fellowship Of Orthopeadic Researchers Inc

BROWN CARTILAGE (CARTILAGE REPAIR & REGENERATION PROGRAM)PATIENTS, WHOSE ACTIVITIES ARE LIMITED DUE TO ARTHRITIC KNEES BUT WHOSE PAIN IS NOT YET SEVERE ENOUGH TO WARRANT A TOTAL KNEE REPLACEMENT, FACE A PAUCITY OF TREATMENT OPTIONS. THE ARTICULAR CARTILAGE REPLACEMENT PROGRAM HAS SUCCESSFULLY DEVELOPED A NOVEL MINIMALLY INVASIVE DEVICE TO REPLACE THE LOST AND DAMAGED CARTILAGE AND BONE IN THE MEDIAL CONDYLE AND THE PATELLA OF THE KNEE IN THESE PATIENTS. THIS TECHNOLOGY HAS BEEN FULLY DEVELOPED INTO A CLINICAL TRIAL READY IMPLANT SYSTEM. DURING 2023, THE FOUNDATION CONTINUED TO EXPLORE PARTNERS AND DONORS TO MAKE THIS TREATMENT AVAILABLE TO PATIENTS. THE INTELLECTUAL PROPERTY DEVELOPED HAS BEEN MAINTAINED AND THE R AND D ACTIVITIES ARE WINDING DOWN. OPPORTUNITIES TO EXPLOIT THE TECHNOLOGY WERE SOUGHT.

BROWN PROSTHESIS (DIRECT TO SKELETON ATTACHMENT PROSTHESIS PROGRAM)THE PROSTHETIC ATTACHMENT PROGRAM DEVELOPED A PROSTHETIC LIMB IN WHICH AN IMPLANT WITHIN THE RESIDUAL LIMB REACTS WITH THE PROSTHETIC SOCKET TO PROVIDE A STABLE, NON-CONTACT CONNECTION BETWEEN THE PATIENT AND THE PROSTHESIS. THE INTERACTION OF THE SPECIALLY DESIGNED MAGNETIC SYSTEMS RESULTS IN A SYSTEM OF FORCES, BY WHICH THE PROSTHESIS AND THE PATIENT'S SKELETON ARE HELD IN MECHANICAL EQUILIBRIUM, ELIMINATING PAIN AND SOFT TISSUE COMPLICATIONS ASSOCIATED WITH TRADITIONAL LIMB PROSTHESES. THIS PROGRAM HAS CONCLUDED AND THE TECHNOLOGY AND KNOWLEDGE GAINED WILL BE TRANSITIONED TO THE MAGNETIC SPINAL APPLICATIONS PROGRAM AS WELL AS SHARED WITH COLLABORATORS. PROTECTION OF INTELLECTUAL PROPERTIES THAT WERE DEVELOPED AS PART OF THIS PROGRAM WILL CONTINUE TO BE AN ONGOING ACTIVITY, HOWEVER, NO EXPENSES WERE INCURRED DURING THE 2023 CALENDAR YEAR.

MAGNETIC SPINAL APPLICATIONS PROGRAM INSTABILITY AND DEGENERATION OF THE SPINE IS A DEBILITATING CONDITION THAT AFFECTS MILLIONS OF PEOPLE. TREATMENTS TYPICALLY INVOLVE SURGICAL STABILIZATION WITH VARYING RESULTS AND WIDE VARIATION IN OUTCOMES. IN 2020, FOR BEGAN RESEARCH AND DEVELOPMENT ON THE MAGNETIC SPINAL APPLICATIONS PROGRAM TO BUILD ON THE TECHNOLOGIES AND APPLY KNOWLEDGE GAINED IN EARLIER RELATED BASIC SCIENCE PROGRAMS. YEAR 2023 ACTIVITIES INCLUDED FURTHER 3-DIMENSIONAL MODELLING OF OPTIMIZED MAGNETIC FIELD CONFIGURATION, SIMULATED IMPLANT DESIGNS, AND THEIR INTERACTIONS WITH MODELS OF THE HUMAN BODY WERE CONDUCTED. OTHER ACTIVITIES AND ACHIEVEMENTS IN 2023 INCLUDED THE DEVELOPMENT AND MANUFACTURE OF A MAGNETIC SYSTEM FOR USE IN THE CERVICAL SPINE. THE REGULATORY STRATEGY WAS IMPLEMENTED AND SAFETY AND EFFICACY TESTING BEGUN ON THE PROTOTYPE SYSTEM. SOURCED VENDORS FOR MAGNETIC MATERIALS AND COATING WERE CONTRACTED AND INITIAL DEVICES DEVELOPED IN COOPERATION.

SCOLIOSIS MAGNETIC SPINE APPLICATION PROGRAM SCOLIOSIS IS A SIDEWAYS CURVATURE OF THE SPINE MOST OFTEN DIAGNOSED IN ADOLESCENTS. THE CAUSE OF MOST SCOLIOSIS IS UNKNOWN AND TERMED "ADOLESCENT IDIOPATHIC SCOLIOSIS OR AIS. IN GENERAL, SCOLIOSIS IS A PROGRESSIVE CONDITION, MEANING THAT IN SOME PATIENTS IT HAS A TENDENCY TO WORSEN WITH AGE WITHOUT CLINICALLY MEANINGFUL INTERVENTION. THE FOR APPROACH TO TREATING AIS IS INTENDED TO REDUCE THE EXTENT AND FREQUENCY OF OPERATIVE INTERVENTIONS, THUS REDUCING THE OVERALL MORBIDITY AND RISK TO THE PATIENT. THE OVERALL GOAL OF THE SCOLIOSIS SPINE PROGRAM IS TO DEVELOP A METHOD TO TREAT AIS USING MAGNET TECHNOLOGY TO CORRECT SPINE CURVATURE AND PREVENT SCOLIOTIC CURVE PROGRESSION. THE SCOLIOSIS PROGRAM BEGAN IN 2023 AND MAJOR ACTIVITIES INCLUDED TRANSITIONING AND BUILDING UPON THE MAGNET SPINE APPLICATIONS TO BE UTILIZED IN THE SCOLIOSIS APPLICATION. IN ADDITION, PROTECTION OF INTELLECTUAL PROPERTIES FOR MAG. SPINE APP. PROGRAM WILL CONTINUE.